P 061 - N,N.N′,N′-tetramethylhydroethidine (TMHE) - in search for better probes for the detection of superoxide radical anion

• Published in: Free radical biology & medicine Vol. 108; p. S38
• Main Authors: Sikora, Adam, Michalski, Radosław, Hardy, Micael, Ouari, Olivier, Jan Adamus, Marcinek, Andrzej, Zielonka, Jacek, Kalyanaraman, Balaraman
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.07.2017
• Subjects: hydroethidine; Superoxide radical anion; Superoxide radical anion; hydroethidine

Superoxide radical anion is a product of one-electron reduction of molecular oxygen. In vivo superoxide radical anion rapidly reacts with nitric oxide with the formation of peroxynitrite (ONOO−) or undergoes spontaneous/SOD-catalyzed dismutation with the formation of hydrogen peroxide (H2O2) and thu...