Identification of prostaglandin E 2 and leukotriene B 4 in the synovial fluid of painful, dysfunctional temporomandibular joints

It has been hypothesized that prostaglandin E 2 (PGE 2) and leukotriene B 4 (LTB 4) should be present in the synovial fluid of inflamed, dysfunctional temporomandibular joints. An assay to identify PGE 2 and LTB 4 and platelet-activating factor (PAF) was used, and a strong correlation between the le...

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Bibliographic Details
Published inJournal of oral and maxillofacial surgery Vol. 48; no. 9; pp. 968 - 971
Main Authors Quinn, James H., Bazan, Nicolas G.
Format Journal Article
LanguageEnglish
Published Elsevier Inc 1990
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Summary:It has been hypothesized that prostaglandin E 2 (PGE 2) and leukotriene B 4 (LTB 4) should be present in the synovial fluid of inflamed, dysfunctional temporomandibular joints. An assay to identify PGE 2 and LTB 4 and platelet-activating factor (PAF) was used, and a strong correlation between the levels of these lipid mediators of pain and inflammation and an index of clinical joint pathology was found.
ISSN:0278-2391
1531-5053
DOI:10.1016/0278-2391(90)90011-P