Plant inhibitors of serine proteinases: hageman factor fragment, kallikreins, plasmin, thrombin, factor X a, trypsin, and chymotrypsin

Numerous plants were tested for inhibitors of human Hageman factor fragment (HF f), plasma kallikrein, urinary kallikrein, plasmin, thrombin, porcine pancreatic kallikrein, and bovine Factor X a, trypsin, and chymotrypsin. Pumpkin seeds and iris bulbs contain trypsin inhibitors which specifically in...

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Bibliographic Details
Published inThrombosis research Vol. 20; no. 2; pp. 163 - 171
Main Authors Hojima, Yoshio, Pierce, Jack V., Pisano, John J.
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 1980
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Summary:Numerous plants were tested for inhibitors of human Hageman factor fragment (HF f), plasma kallikrein, urinary kallikrein, plasmin, thrombin, porcine pancreatic kallikrein, and bovine Factor X a, trypsin, and chymotrypsin. Pumpkin seeds and iris bulbs contain trypsin inhibitors which specifically inhibit HF f. Flower bulbs—especially those of tulip, lily, hyacinth, and calla—are hitherto unrecognized rich sources of inhibitors with different inhibitory spectrums and physicochemical properties.
ISSN:0049-3848
1879-2472
DOI:10.1016/0049-3848(80)90382-5