Defective 30S ribosomal particles in a polyamine auxotroph of [formula omitted]
Polypeptide synthesis directed by poly(U) or MS 2 phage RNA is several fold more active in cell-free systems prepared from polyamine supplemented bacteria than in extracts of polyamine depleted cells. This effect depends on the presence of defective 30S ribosomal subunits in the starved bacteria. It...
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Published in | Biochemical and biophysical research communications Vol. 67; no. 3; pp. 1185 - 1191 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Elsevier Inc
1975
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Subjects | |
Online Access | Get full text |
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Summary: | Polypeptide synthesis directed by poly(U) or MS 2 phage RNA is several fold more active in cell-free systems prepared from polyamine supplemented bacteria than in extracts of polyamine depleted cells. This effect depends on the presence of defective 30S ribosomal subunits in the starved bacteria. It is concluded that polyamines play a role in the normal biosynthesis, maturation and/or assembly of the small ribosomal subparticles. |
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ISSN: | 0006-291X 1090-2104 |
DOI: | 10.1016/0006-291X(75)90798-6 |