Defective 30S ribosomal particles in a polyamine auxotroph of [formula omitted]

Polypeptide synthesis directed by poly(U) or MS 2 phage RNA is several fold more active in cell-free systems prepared from polyamine supplemented bacteria than in extracts of polyamine depleted cells. This effect depends on the presence of defective 30S ribosomal subunits in the starved bacteria. It...

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Bibliographic Details
Published inBiochemical and biophysical research communications Vol. 67; no. 3; pp. 1185 - 1191
Main Authors Echandi, G., Algranati, I.D.
Format Journal Article
LanguageEnglish
Published Elsevier Inc 1975
Subjects
minimal medium containing ornithine (100 μg/ml)
MMOP
minimal medium with putrescine (100 μg/ml, each)
minimal medium with ornithine
MMO
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Summary:Polypeptide synthesis directed by poly(U) or MS 2 phage RNA is several fold more active in cell-free systems prepared from polyamine supplemented bacteria than in extracts of polyamine depleted cells. This effect depends on the presence of defective 30S ribosomal subunits in the starved bacteria. It is concluded that polyamines play a role in the normal biosynthesis, maturation and/or assembly of the small ribosomal subparticles.
ISSN:0006-291X
1090-2104
DOI:10.1016/0006-291X(75)90798-6