Squamous Cell Carcinoma of the Scrotum Following Brachytherapy and External Beam Radiotherapy for Prostate Cancer: Case Report and Review of the Literature

Abstract Secondary primary cancer development following radiotherapy for prostate cancer is a rare but well documented occurrence. However, there are few reported cases of in-field cutaneous secondary malignancies. We report a case of stage II squamous cell 12 years following radiotherapy for prosta...

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Bibliographic Details
Published inClinical genitourinary cancer
Main Authors Glaser, Zachary A, White, Matthew, Mckinley, Elizabeth, Glaser, Jeffrey S
Format Journal Article
LanguageEnglish
Published 2016
Subjects
Hematology, Oncology and Palliative Medicine
Urology
external beam radiotherapy
prostate cancer
brachytherapy
squamous cell carcinoma
second primary cancer
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Summary:Abstract Secondary primary cancer development following radiotherapy for prostate cancer is a rare but well documented occurrence. However, there are few reported cases of in-field cutaneous secondary malignancies. We report a case of stage II squamous cell 12 years following radiotherapy for prostate cancer. We also review relevant literature available to date. An 83-year-old Asian male presented to clinic with a growth on his left scrotum. His past medical history was significant for prostate cancer of unknown pathology for which he received external beam radiotherapy with brachytherapy. He underwent excision of the mass and imaging for disease staging. He is currently disease-free. It is unclear whether this patient’s cutaneous malignancy developed secondary to in-field radiation exposure or to a separate underlying cause.
ISSN:1558-7673
DOI:10.1016/j.clgc.2016.08.007