Correlation between Serum Uric Acid/Creatinine Ratio and Metabolism-associated Fatty Liver Disease

• Published in: Zhongguo quanke yixue Vol. 27; no. 20; pp. 2476 - 2482
• Main Author: HOU Nana, FENG Jinzhang, LIU Suohong, FENG Junfang, XUE Xiaoyan, YIN Na, CHI Gefu
• Format: Journal Article
• Language: Chinese
• Published: Chinese General Practice Publishing House Co., Ltd 01.07.2024
• Subjects: non-alcoholic fatty liver disease|metabolically associated fatty liver disease|sua/cr|uric acid|root cause analysis
• ISSN: 1007-9572
• DOI: 10.12114/j.issn.1007-9572.2023.0837

Background Metabolic associated fatty liver disease (MAFLD) is more prevalent than non-alcoholic fatty liver disease (NAFLD), leading to the identification of a variety of metabolically complex fatty liver diseases. The serum uric acid/creatinine ratio (SUA/Cr) is a new biomarker discovered after renal function-normalized SUA. At present, there have been few studies on the relationship between SUA/Cr and MAFLD. Objective To explore the correlation of SUA/Cr with MAFLD, and its predictive value for MAFLD. Methods We enrolled 2 288 individuals who visited the Physical examination Center of the Affiliated Hospital of Inner Mongolia Medical University in February to June 2023. Venous blood samples were collected for laboratory tests, and abdominal ultrasonography was used to examine the liver condition. Based on the results of abdominal ultrasonography and the diagnostic criteria for MAFLD, the subjects were divided into the MAFLD group (n=945) and non-MAFLD group (n=1 343). According to SUA/Cr quartiles, the sub