Antimicrobial resistance of nosocomial Staphylococcus aureus isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

The study included 418 of the 841 clinical isolates of S. aureus, which were regarded as nosocomial. These 418 clinical nosocomial S. aureus strains were isolated in 2013-2014 from patients hospitalized in 25 hospitals in 19 Russian cities. Methicillin-resistance rate was 24.9% (n=104). Antimicrobia...

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Published inKlinicheskai︠a︡ mikrobiologii︠a︡ i antimikrobnai︠a︡ khimioterapii︠a Vol. 19; no. 1; pp. 57 - 62
Main Authors Romanov A.V., Dekhnich A.V., Sukhorukova M.V., Skleenova E.Yu, Ivanchik N.V., Edelstein M.V., Kozlov R.S., «MARATHON» Study Group
Format Journal Article
LanguageRussian
Published Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy 01.02.2017
Subjects
antimicrobial resistance
mrsa
nosocomial infections
staphylococcus aureus
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Summary:The study included 418 of the 841 clinical isolates of S. aureus, which were regarded as nosocomial. These 418 clinical nosocomial S. aureus strains were isolated in 2013-2014 from patients hospitalized in 25 hospitals in 19 Russian cities. Methicillin-resistance rate was 24.9% (n=104). Antimicrobials with the highest activity with no resistance detected were vancomycin, linezolid, cefilavancin, telavancin, daptomycine, tigecycline and fusidic acid. Other highly in-vitro active antimicrobials were trimethoprim-sulfamethoxazole, mupirocin and ceftaroline (0.5%, 2.2% and 4.3% non-susceptible isolates respectively). MRSA isolates were substantially less susceptible compare with MSSA to gentamicin (1.3% vs. 83.7%), clindamycin (1.6% vs. 40.4%), rifampicin (2.2% vs. 27.9%), tetracycline (12.1% vs. 35.6%), chloramphenicol (9.9% vs. 71.2%), ceftaroline (0% vs. 17.3%), ciprofloxacin (6.1% vs. 89.4%), and erythromycin (18.5% vs. 58.7%).
ISSN:1684-4386
2686-9586