The course and out-come of a pregnancy superimposing untreated Graves' thyrotoxicosis

Objective: The objective of this case report is to highlight the occurrence of a pregnancy in an African woman with untreated Graves' thyrotoxicosis; there being a virtual absence in the literature of reports about similar observations in humans. Case report: Described here is one case of a pre...

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Bibliographic Details
Published inInternational Journal of Medicine and Health Development Vol. 6; no. 1; pp. 51 - 52
Main Authors A U Mbah, J M Okaro
Format Journal Article
LanguageEnglish
Published Wolters Kluwer Medknow Publications 01.01.2001
Subjects
graves' disease
pregnancy
pregnancy outcome
thyrotoxicosis
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Summary:Objective: The objective of this case report is to highlight the occurrence of a pregnancy in an African woman with untreated Graves' thyrotoxicosis; there being a virtual absence in the literature of reports about similar observations in humans. Case report: Described here is one case of a pregnancy that occurred in a Nigerian woman with unrecognized Graves' thyrotoxicosis. The pregnancy was carried until the 25th week before thyrotoxicosis was correctly diagnosed and antithyroid therapy instituted. Aspects of the course and out-come of the pregnancy relevant to the current understanding of the relationship between maternal thyroid hyper function and foetal development are discussed. Conclusion: It is concluded that the mechanisms involved in the adverse foetal developmental effects of thyrotoxicosis in pregnancy are complex and yet to be fully understood.
ISSN:2635-3695