An investigation of Helicobacter pylori infection and potential risk factors of colonization found in 10 661 cases from routine physical examination

• Published in: Ji chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics Vol. 42; no. 1; pp. 126 - 130
• Main Author: LEI Rong, YANG Dan, YUAN Fang-tao, ZHOU Xiao-yan, JIANG Yi-min, LIU Mi
• Format: Journal Article
• Language: Chinese
• Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College 01.01.2022
• Subjects: helicobacter pylori|carbon13-urea breath test (13c-ubt)|risk factors|correlation
• ISSN: 1001-6325
• DOI: 10.16352/j.issn.1001-6325.2022.01.019

Objective To investigate the situation of Helicobacter pylori(H.pylori) infection in healthy people and analyze the related risk factors. Methods Retrospective analysis was conducted on 10 661 healthy subjects who underwent carbon 13-urea breath test (13C-UBT)on January 1, 2019 to December 30, 2020 in affiliated hospital of North Sichuan Medical College. According to the infection status of Helicobacter pylori (H.pylori), the subjects were divided into H.pylori positive group and H.pylori negative group. H.pylori infection and platelet (PLT), triglyceride(TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG), T3, T4, TSH and pepsinogen Ⅰ (pepsinogen Ⅰ) were analyzed. PepsinogenⅠ, pepsinogen Ⅱ(pepsinogen), gastrin 17(G-17), homocysteine (Hcy), uric acid (UA) and total bilirubin (TBIL)were also examined. Results 1)The total number of positive infections: 4 382, the total positive rate: 41.10%, including 2 717 male posi