Squamous cell carcinoma of the thyroid gland: the analysis of primary and secondary disease

• Published in: Ji chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics Vol. 41; no. 4; pp. 562 - 567
• Main Author: JIN Chao, LIU Gang, XU Xie-qun
• Format: Journal Article
• Language: Chinese
• Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College 01.04.2021
• Subjects: thyroid|squamous cell carcinoma|cancer|head and neck|papillary thyroid carcinoma
• ISSN: 1001-6325

Objective To discuss the clinical characteristics of patients with primary squamous cell carcinoma of the thyroid(PSCCT) and secondary squamous cell carcinoma of the thyroid(SSCCT). Methods The medical records of 17 PSCCT patients and 6 SSCCT patients admitted to Peking Union Medical College Hospital were systematically reviewed.Clinical symptoms, ultrasound, and pathological characteristics were compared between the two groups. Results The percentage of the female was higher than male and the mean age of diagnosis was about 56 years old in each group. The most common chief complaint of the patients was neck mass in both groups. The percentage of patients with cough(P＜0.01) was higher in SSCCT group than PSCCT group. The mean size of the tumor in PSCCT group was larger than SSCCT group(P＜0.05). Papillary thyroid carcinoma (PTC) could be complicated with or recurrent as PSCCT. The mean survival time after diagnosis was 17.1 months in the PSCCT patients and 13.5 months in the SSCCT patients. Predictors of overa