Immunological features of secernating breasts

• Published in: Opukholi zhenskoĭ reproduktivnoĭ sistemy no. 4; pp. 46 - 50
• Main Authors: G. Kh. Khanafiev, S. A. Berzin
• Format: Journal Article
• Language: Russian
• Published: ABV-press 01.01.2015
• Subjects: galactoforit; lactostasis; proliferation; secernire the mammary gland; the immune response to the bacteriological antigen
• ISSN: 1994-4098; 1999-8627
• DOI: 10.17650/1994-4098-2014-0-4-46-50

From 122 (100 %) of women with aseptic discharge from breast milk glands in 42.6 % of the cases in history was celebrated mastitis, in 25.4 % – postpartum lactostasis. Study of the immune status of these women have found that for secernire of mammary glands is more characteristic of differentiation on the grounds of proliferation and autoimmunization (reduction of immunoglobulin classes M and G, decrease subset of T-helper (CD4) and T-uppressor (CD8) cells, immune deficiency according to the T-cell and fagocitare links), as well as on the grounds of chronic inflammatory process (a high content of Ig class A, increase subset of CD8 cells with marker of apoptosis (CD95)). Increasing of immunoglobulin class G-outside of the panel evidences of the development of the immune answer to the bacteriological or viral antigen. Moderate deficiency of phagocyte, increase of interleukin decrease subpopulations CD3, the reduction ratio of CD4/CD8 testifies to inflammatory process.