Research progress on regulatory mechanisms of circular RNA nuclear receptor interacting protein 1 in tumor occurrence and development

Circular RNA (circRNA) is a class of single-stranded covalently closed non-coding RNA molecules widely expressed in eukaryotic cells. Recent studies have found that circRNA has been involved in modulating biological processes such as cell proliferation, differentiation, and apoptosis so it is the ke...

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Published inJi chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics Vol. 43; no. 5; pp. 827 - 832
Main Author GAO Xin, YU Yongbo, WANG Haicun, JIANG Xingming, WANG Zhidong
Format Journal Article
LanguageChinese
Published Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College 01.05.2023
Subjects
circular rna|circular rna nuclear receptor interacting protein 1(circ_nrip1)|tumor occurrence and development|regulatory mechanism
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Summary:Circular RNA (circRNA) is a class of single-stranded covalently closed non-coding RNA molecules widely expressed in eukaryotic cells. Recent studies have found that circRNA has been involved in modulating biological processes such as cell proliferation, differentiation, and apoptosis so it is the key regulator of tumor occurrence and development. Circular RNA nuclear receptor interacting protein 1(circ_NRIP1), as a circular RNA, is abnormally expressed in various human cancers and potentially regulates malignant biological behaviors such as tumor proliferation, invasion and migration. Elucidating the regulatory mechanisms of circ_NRIP1 in tumor occurrence and development may provide a new strategy for tumor diagnosis and treatment.
ISSN:1001-6325
DOI:10.16352/j.issn.1001-6325.2023.05.0827