A Comparative study on the prevalence of HCC seromarkers among tribal and coastal population

An extensive study on the prevalence of seromarkers (HBsAg and AFP) of hepatocellular carcinoma among two low socioeconomic groups of Karumanthurai tribes and Kanyakumari coastal population was carried out. The results obtained suggest that the mean HBsAg value of tribal was more than that of the co...

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Bibliographic Details
Published inIranica journal of energy & environment Vol. 1; no. 3; pp. 179 - 183
Main Authors Joseph Selvin, Aseer Manilal, C. Rani, B. Sabarathnam, G. Seghal Kiran, Sujith Sugathan, Chippu Shakir
Format Journal Article
LanguageEnglish
Published Babol Noshirvani University of Technology 01.03.2010
Subjects
AFP
HBsAg
HBV
Hepatocellular carcinoma
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Summary:An extensive study on the prevalence of seromarkers (HBsAg and AFP) of hepatocellular carcinoma among two low socioeconomic groups of Karumanthurai tribes and Kanyakumari coastal population was carried out. The results obtained suggest that the mean HBsAg value of tribal was more than that of the coastal population. The mean AFP of elevated and normal cases was found to be invariably significant (P< 0.01) over the two areas. Coastal patients tended to be significantly older than the tribal patients (P < 0.005, Wilcoxon rank sum test). All two racial/geographic regions showed a preponderance of male patients but this tendency was significantly more marked (P < 0.05) in the tribal group than in the coastal sample. Liquor habit and lack of personal hygienic practices were associated with the prevalence of HBsAg and AFP in both the areas. Surprisingly a positive association has been found between the consumption of marine foods and reduced risk of HCC. Thus the reduced risk of HCC among coastal population can probably be due to the development of immunity against HBV due to the dietary pattern of marine food consumption by coastal population.
ISSN:2079-2115
2079-2123