Cytokines balance change in gingival fluid at periodontal diseases and its value for the prognosis of regeneration disturbances in periodontal tissues

Purpose: To establish diagnostic value of the increased content of pro- and anti-inflammatory cytokines (IL-8, MCP-1, RAIL) in gingival fluid at patients with a chronic periodontal disease. Material and Methods: 60 patients with inflammatory periodontal diseases were surveyed. The concentration of t...

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Published inSaratovskiĭ nauchno-medit͡s︡inskiĭ zhurnal Vol. 10; no. 3; pp. 435 - 440
Main Authors Ostrovskaya L.Yu, Zakharova N.B., Mogila А.Р., Katkhanova L.S., Akulova E.V., Popykhova E.B.
Format Journal Article
LanguageRussian
Published Saratov State Medical University 01.09.2014
Subjects
cytokines
gingival fluid
periodontal disease
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Summary:Purpose: To establish diagnostic value of the increased content of pro- and anti-inflammatory cytokines (IL-8, MCP-1, RAIL) in gingival fluid at patients with a chronic periodontal disease. Material and Methods: 60 patients with inflammatory periodontal diseases were surveyed. The concentration of the studied cytokines in gingival fluid has been defined. Results: At a periodontal disease the increased level of pro- and anti-inflammatory cytokines in gingival fluid has been noted. Conclusion: Definition of the MCP-1 and IL-8 levels in gingival fluid can be used as a criterion of the prognosis of the severity of inflammatory and destructive processes in the periodontal tissues.
ISSN:2076-2518