Effect of subclinical hypothyroidism on endocrine and metabolic characteristics of patients with polycystic ovary syndrome

• Published in: Ji chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics Vol. 43; no. 4; pp. 641 - 646
• Main Author: ZHANG Yuanmou, HAN Kang, XIA Rui, SUN Wenjian, REN Xiaoying, WANG Yan
• Format: Journal Article
• Language: Chinese
• Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College 01.04.2023
• Subjects: polycystic ovary syndrome|subclinical hypothyroidism|thyroid stimulating hormone|abnormal lipid metabolism|insulin resistance
• ISSN: 1001-6325
• DOI: 10.16352/j.issn.1001-6325.2023.04.0641

Objective To analyze the effect of subclinical hypothyroidism(SCH)on endocrine and metabolic characteristics of polycystic ovary syndrome(PCOS)patients, and to explore the correlation between thyroid stimulating hormone (TSH) level and various endocrine and metabolic indexes. Methods Totally 661 patients with PCOS in the outpatient Department of Endocrinology and Metabolism of the First People's Hospital of Yunnan Province from January 2020 to June 2021 were selected as the research object. The general data and related endocrine and metabolic indexes of the patients were collected. Taking the TSH value of 4.2 mIU/L as the cut-off point for the diagnosis of SCH, PCOS patients were divided into SCH group and non SCH group. The differences of endocrine and metabolic characteristics between the two groups were compared; The correlation between TSH level and its endocrine and metabolic indexes was analyzed. Results The incidence of SCH in PCOS patients was 31.16%. Compared with PCOS patients without SCH, the level