Clinicopathological features of 2 cases of squamous cell carcinoma and 2 cases of adenosquamous carcinoma

• Published in: Zhenduanxue Lilun yu Shijian Vol. 22; no. 1; pp. 44 - 49
• Main Author: WANG Han, LU Haidi, WANG Lei, CONG Wenming, ZHENG Jianming, BAI Chenguang
• Format: Journal Article
• Language: Chinese
• Published: Editorial Office of Journal of Diagnostics Concepts & Practice 01.02.2023
• Subjects: squamous cell carcinoma|colorectal cancer|prognosis
• ISSN: 1671-2870
• DOI: 10.16150/j.1671-2870.2023.01.007

Objective: To investigate the clinicopathological features of colon squamous cell carcinoma and adenosquamous carcinoma. Methods: The clinicopathological data and prognosis of 4 patients with colonic squamous cell carcinoma or adenosquamous carcinoma were collected retrospectively. Results: There were 1 male and 3 female, and the age ranged from 29 to 76 years old. Serum CA19-9 was increased in 2 cases, which were 88.25 ng/mL and 553.13 ng/mL, respectively. Serum CEA increased in 2 cases, which were 116.39 U/mL and 37.22 U/mL, respectively. Three cases occurred in ascending colon and 1 case in descending colon. Microscopically, the squamous cell carcinoma of 4 cases was arranged into irregular nesting or flake shape, the tumor cells were polygonal or irregular, the cells were eosinophilic and expressed P40 and P63, while the adenocarcinoma of 2 adenosquamous carcinoma cases was arranged into irregular glandular tubules or cribriform, and the cell nucleus was deeply stained and expressed CAM5.2 and CK20. P16 w