Diagnostic value of ET-1 and UA in early kidney injury of pregnancy-induced hypertension

Objective To observe the diagnostic value of endothelin-1(ET-1) and uric acid(UA) in early kidney injury of pregnancy-induced hypertension(PIH).Methods From January 2010 to January 2016,303 PIH patients were enrolled to the Obstetrics and Gynecology Department of Wuhan Medical & Healthcare Cente...

Full description

Saved in:
Bibliographic Details
Published inLinchuang Shenzangbing Zazhi pp. 32 - 35
Main Authors 蔡静, 张丹
Format Journal Article
LanguageChinese
Published Editorial Department of Journal of Clinical Nephrology 01.01.2017
Subjects
Diagnostic value
Early kidney injury
Endothelin-1
Uric acid
Online AccessGet full text

Cover

More Information
Summary:Objective To observe the diagnostic value of endothelin-1(ET-1) and uric acid(UA) in early kidney injury of pregnancy-induced hypertension(PIH).Methods From January 2010 to January 2016,303 PIH patients were enrolled to the Obstetrics and Gynecology Department of Wuhan Medical & Healthcare Center for Women and Children as PIH group,and 100 normal pregnant women served as control group.PIH group was assigned into mild with 124 cases,moderate 97 cases and severe 82 cases according to the severity of PIH.Then PIH patients were also divided into two groups:kidney injury group(n= 112) and normal group(n = 191) based on the kidney functioa The relationship between the levels ET-1,UA with the severity of PIH and kidney injury was observed.The diagnostic value was verified on the risk factors by receiver operating characteristic(ROC) curve.Results The levels of ET-1 and UA in PIH group were significantly higher than in the control group(P<0.01).The levels of ET-1 and UA were related to the severity of PIH.Univariate
ISSN:1671-2390