The symptoms of gastroesophegeal reflux disease

• Published in: Turkish Archives of Otorhinolaryngology Vol. 43; no. 1; pp. 20 - 25
• Main Authors: Emin Karaman, Engin Acıoğlu, Aydın Mamak, Ferhan Öz
• Format: Journal Article
• Language: English
• Published: Galenos Yayincilik 01.03.2005
• Subjects: gastroesophageal reflux; laryngopharyngeal symptoms; ph monitoring
• ISSN: 2667-7474

Objectives:Gastroesophegeal reflux disease were determined with 24 hour pH monitorization in a selected group of patient and laryngopharyngeal symptoms frequency of them were evaluated with the current literature.Methods:The study included 27 patients (15 male, 12 female; range 22 to 82 years; mean age 48.1 years) with the diagnosis of gastroesophageal reflux disease via 24 hour pH monitorization and 10 patients (6 male, 4 female; range 27 to 67 years; mean age 44.5 years) as control group. Both patient groups were monitorized for 24 hour and distal esophageal pH was measured periodically once every 4 seconds. Decreasing of the distal esophageal pH less than four was accepted the beginning of the reflux. Contrary, increasing of the distal esophageal pH more than four was accepted the ending of the reflux. The percentage of the time, in which the esophageal pH is less than 4 during which the patients were standing and in the supine position, to the total time was determined and compared. In addition, laryngopharyngeal symptoms of the gastroesophageal reflux disease were evaluated in the patient group.Results:In the control group, The percentages were 7.14% in standing position, 4.83% in supine position and 5.42% for the total time. The percentages for the 27 patients were 27.5%, 30.5% and 28.3%, respectively. In the patient group, 17 patients (62.9%) had heartburn and/or regurgitation, 14 patients (51.9%) had cough, 18 patients (66.6%) had hoarseness, 22 patients (81.5%) had frequently throat clearing, 16 patients (59.3%) had excessive secretion to the throat, 14 patients (51.9%) had dysphagia, 21 patients (77.7%) had globus and 2 patients (7.4%) had dyspnea.Conclusion:We must remember probable gastroesophageal reflux disease with the existence of atypic symptoms such as hoarseness, cough, dysphagia, globus, excessive secretion to the throat and frequently throat clearing probable and we must perform 24 hour pH monitorization for the diagnosis.