In vitro Efficacy of Ingavirin® against the Pandemic Influenza Virus A(H1N1/09)v

Ingavirin® was shown to be efficient in inhibition of the influenza virus strains A/California/04/2009 (H1N1)v, A/California/07/2009 (H1N1)v, A/Moscow/225/2009 (H1N1)v and A/Moscow/226/2009 (H1N1)v, as well as the strains A/Chicken/Kurgan/05/2005 (H5N1) and A/Aichi/2/68 (H3N2) in the MDCK cell cultu...

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Published inАнтибиотики и Химиотерапия Vol. 55; no. 3-4; pp. 12 - 16
Main Authors L. N. Shishkina, V. E. Nebolsin, A. S. Kabanov, M. O. Skarnovich, U. B. Erdyneeva, N. A. Mazurkova, O. A. Serova, E. A. Stavsky, I. G. Drozdov
Format Journal Article
LanguageRussian
Published LLC "Publishing House OKI" 01.05.2020
Subjects
antiviral activity
influenza virus a(h1n1/09)v
ingavirin
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Summary:Ingavirin® was shown to be efficient in inhibition of the influenza virus strains A/California/04/2009 (H1N1)v, A/California/07/2009 (H1N1)v, A/Moscow/225/2009 (H1N1)v and A/Moscow/226/2009 (H1N1)v, as well as the strains A/Chicken/Kurgan/05/2005 (H5N1) and A/Aichi/2/68 (H3N2) in the MDCK cell culture. The hemagglutinin and cytopathic activity of the influenza virus strains decreased at entering Ingavirin® in vitro.
ISSN:0235-2990