Research Progress of Traditional Chinese and Western Medicine in the Treatment of Irritable Bowel Syndrome Based on 5-hydroxytryptamine

Irritable bowel syndrome (IBS) is a gastrointestinal disorder with no structural damage and biochemical abnormality, and its pathogenic mechanism is still unclear. Variety of drugs, psychotherapy, diet regulation and other methods have been used by modern medicine to relieve symptoms, but the effect...

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Bibliographic Details
Published inZhongguo quanke yixue Vol. 25; no. 15; pp. 1800 - 1806
Main Author Pengning WU, Shuai XIONG, Xiaohan JIANG, Yi ZHANG, Chao LIANG, Min CHEN
Format Journal Article
LanguageChinese
Published Chinese General Practice Publishing House Co., Ltd 01.05.2022
Subjects
irritable bowel syndrome|5-hydroxytryptamine|serotonin|integrated traditional chinese medicine & western medicine|therapy|review
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Summary:Irritable bowel syndrome (IBS) is a gastrointestinal disorder with no structural damage and biochemical abnormality, and its pathogenic mechanism is still unclear. Variety of drugs, psychotherapy, diet regulation and other methods have been used by modern medicine to relieve symptoms, but the effect is not satisfactory. In recent years, TCM treatment of IBS has attracted widespread attention, especially for constipation type and diarrhea type. Among the many experiments, most of the traditional Chinese medicine experiments aimed at the 5-HT signaling pathway have achieved good results. Therefore, this paper summarizes the main mechanisms and results of traditional Chinese medicine based on 5-HT in the treatment of IBS, in order to provide a reference for subsequent research.
ISSN:1007-9572
DOI:10.12114/j.issn.1007-9572.2022.0034