Design, Synthesis and Antiviral Potential of 14-Aryl/Heteroaryl-14 em>H /em>-dibenzo em>[a,j] /em>xanthenes Using an Efficient Polymer-Supported Catalyst

Polyethyleneglycol bound sulfonic acid (PEG-OSO 3 H), a chlorosulphonic acid-modified polyethylene glycol was successfully used as an efficient and eco-friendly polymeric catalyst in the synthesis of 14-aryl/heteroaryl-14 H -dibenzo[ a,j ]xanthenes obtained from the reaction of 2-naphthol and carbon...

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Bibliographic Details
Published inMolecules (Basel, Switzerland) Vol. 17; no. 6; pp. 7543 - 7555
Main Authors Ola Lasekan, Mungara Anil Kumar, Palanisamy Arulselvan, Shaik Ibrahim Khalivulla, Balam Satheesh Krishna, Kalla Reddi Mohan Naidu
Format Journal Article
LanguageEnglish
Published MDPI AG 01.06.2012
Subjects
2-naphthol
aryl aldehydes
neat reaction
PEG-OSO 3 H
tobacco mosaic virus
xanthenes
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Summary:Polyethyleneglycol bound sulfonic acid (PEG-OSO 3 H), a chlorosulphonic acid-modified polyethylene glycol was successfully used as an efficient and eco-friendly polymeric catalyst in the synthesis of 14-aryl/heteroaryl-14 H -dibenzo[ a,j ]xanthenes obtained from the reaction of 2-naphthol and carbonyl compounds under solvent-free conditions with short reaction times and excellent yields. The biological properties of these synthesized title compounds revealed that compounds 3b , 3c , 3f and 3i showed highly significant anti-viral activity against tobacco mosaic virus.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules17067543