Estudo de seroprevalência da infecção por vírus Toscânia na região do Porto

Toscana virus (TOSV) endemic in central Italy, has been documented in several European countries of the Mediterranean region. It is a neurotropic virus and in some of these countries studies to investigate seroprevalence have been done. In a recent etiologic study of meningitis we chose 106 of 308 s...

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Bibliographic Details
Published inActa médica portuguesa Vol. 24
Main Authors Lurdes Santos, Maria João Cardoso, Ana Sofia Marinho, Tiago Guimarães, António Sarmento
Format Journal Article
LanguageEnglish
Published Ordem dos Médicos 01.12.2011
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Summary:Toscana virus (TOSV) endemic in central Italy, has been documented in several European countries of the Mediterranean region. It is a neurotropic virus and in some of these countries studies to investigate seroprevalence have been done. In a recent etiologic study of meningitis we chose 106 of 308 samples to be tested for TOSV using a nested RT-PCR assay, and found six (5.6%) cases of meningitis by Toscana virus.To investigate the seroprevalence of antibodies against TOSV in a cohort of a population attended in our Hospital.In serum samples collected for routine study we have investigated the presence of antibodies for TOSV. The study included samples of patients hospitalized and others observed in ambulatory and includes children and adults. Immunocompromised patients were excluded. The test was based on the-ELISA technique ((ENZYWELL), according to the manufacture instructions, being positive for a cut-off>1.2, negative if the cut-off 0.8 e
ISSN:0870-399X
1646-0758
DOI:10.20344/amp.1446