Epidemiological features Delta together multiple infection in Saint-Petersburg

• Published in: Zhurnal infektologii Vol. 7; no. 3; pp. 119 - 125
• Main Authors: V. V. Nechaev, I. P. Fedunyak, M. N. Pogromskaja, L. L. Scherbak, L. N. Pozhidaeva, V. V. Dievskaya, A. F. Gronberg, I. A. Hmelkova, Yu. M. Schkwarok, A. K. Ivanov
• Format: Journal Article
• Language: Russian
• Published: Journal Infectology 01.11.2015
• Subjects: delta co-infection; epidemiological features
• ISSN: 2072-6732
• DOI: 10.22625/2072-6732-2015-7-3-119-125

Studied the epidemiological features of the delta as a coinfection of hepatitis B in Saint-Petersburg for 14-year period (2002–2014). Clinical and laboratory data of 232 patients admitted to Botkin CIB them during this period. Revealed a 2-fold increase in performance of co-infection (Br + + IOP HIV) by 2014. In 49,6% of patients (group 1) were diagnosed less often chronic and acute forms of HBV in combination with delta infection. In 24,5% of cases (group 2) delta infection is associated with chronic hepatitis B and C. In the remaining 25,9% of the cases (B group) occurred multiple infection(HBV + HCV + HIV + IOP). Based on the clinical and epidemiological and laboratory data in 75,8% of patients defined delta superinfection, at 24,2% – co-infection. The marked increase in co-delta infection in recent years due to the accumulation of the potential epidemic of chronic hepatitis B in the population and the increase in the number of imported cases from 8,8% to 37,2% of migrants in the city. Cytolytic components, characterized by higher rates of ALT activity was most pronounced in the first group and the third group is minimal. However, the mean activity values for patients of the 3rd group were higher than in the first. ACAT groups had the same tendency as AlAt. Patients third group was a higher mortality, compared with other groups.