Preparation of an amino hybrid mesoporous silica-based nanotopography protective coating on a titanium implant surface and evaluation of its osteogenic effect
Objective To deposit degradable amino-hybrid mesoporous silica (AHMS) in situ on the surface of titanium nanotube (TNT) and explore its protective effect on nanomorphology and osteogenesis. Methods TNT and TNT@AHMS were sequentially prepared via an anodizing method: the oil-water two-phase method (e...
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Published in | Kou qiang ji bing fang zhi = Journal of prevention and treatment for stomatological diseases Vol. 32; no. 5; pp. 341 - 349 |
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Main Authors | , , , |
Format | Journal Article |
Language | Chinese |
Published |
Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
01.05.2024
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Subjects | |
Online Access | Get full text |
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Summary: | Objective To deposit degradable amino-hybrid mesoporous silica (AHMS) in situ on the surface of titanium nanotube (TNT) and explore its protective effect on nanomorphology and osteogenesis. Methods TNT and TNT@AHMS were sequentially prepared via an anodizing method: the oil-water two-phase method (experimental group) and the acid-etched titanium method [control group (Ti)]. The parameters for synthesis were explored by changing the silicon source dosage ratio (3∶1, 1∶1, 1∶3); the surface morphology was observed by scanning electron microscope(SEM), hydrophilicity was detected by Water Contact Angle Tester, elemental composition was detected by X-ray photoelectron spectroscopy (XPS); nanoindentation test and ultrasonic oscillator were used to observe the morphological holding effect as mechanical strength of TNT@AHMS in vitro; simulated immersion experiments in vitro was used to observe the degradation behavior of the material. the MC3T3-E1 cell line was used to observe the effect of cell adhesion, proliferati |
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ISSN: | 2096-1456 |
DOI: | 10.12016/j.issn.2096⁃1456.2024.05.003 |