Efficiency and tolerance of acne therapy using system isotretinoin

• Published in: Vestnik dermatologij i venerologij no. 5; pp. 128 - 133
• Main Authors: Yu. N. Perlamutrov, K. B. Olkhovskaya, M. M. Kokhan, Yu. V. Keniksfest, Yu. B. Shaibakova, N. V. Polyakova, E. P. Topychkanova, Ya. V. Kashcheeva, A. V. Samtsov, A. V. Statsenko, I. E. Belousova, V. R. Khayrutdinov, S. V. Volkova, A. S. Zhukov
• Format: Journal Article
• Language: English
• Published: State Scientific Center of Dermatovenereology and Cosmetology 01.08.2017
• Subjects: achieving clinical remission; acne conglobate; acne inversa; isotretinoin; low risk of serious adverse events; moderate and severe acne; sotret; акне средней и тяжелой степени тяжести; достижение клинической ремиссии; изотретиноин; инверсные акне; конглобатные акне; низкий риск серьезных нежелательных явлений; сотрет
• ISSN: 0042-4609; 2313-6294
• DOI: 10.25208/0042-4609-2015-0-5-128-133

Purpose. Determination of efficiency and tolerance of Sotret product in treatment of patients with different clinical forms and severe acne in three clinical investigations. Materials and methods. 103 patients with acne (moderate and severe acne, acne conglobata and acne inversa) were examined and treated. All patients underwent monotherapy with Sotret with clinical effectiveness assessment and records of adverse events. Results. Sotret therapy facilitated clinical remission of acne in 90-100% of cases. Adverse events were easily tolerated and were not serious. Conclusion. Established therapeutic efficiency of Sotret determines its potential in treating various severity and various forms of acne.