The aromatase expression in myomas and myometriums of women in reproduction and perimenopausal age

Uterine myomas represent one of the most common female pathologies. Uterine smooth muscle myomas or fibromas are benign tumours which respond to hormones and their etiology induces wide interest. The myomas were found to contain aromatase and, in addition, cells of the myomas were found to synthesiz...

Full description

Saved in:
Bibliographic Details
Published inFolia histochemica et cytobiologica Vol. 47; no. 3; pp. 497 - 504
Main Authors Edyta Bogunia, Grazyna Nowaczyk, Piotr Paleń, Danuta Plewka, Andrzej Plewka, Paweł Madej, Jacek Marczyński, Józef Waloszek
Format Journal Article
LanguageEnglish
Published Via Medica 01.02.2010
Online AccessGet full text

Cover

More Information
Summary:Uterine myomas represent one of the most common female pathologies. Uterine smooth muscle myomas or fibromas are benign tumours which respond to hormones and their etiology induces wide interest. The myomas were found to contain aromatase and, in addition, cells of the myomas were found to synthesize estrogen. This study was conducted on patients with the myomas, in either generative age or in the perimenopausal period. Expression of aromatase was detected in patients of various age, with large or small uterine myomas, using an immunohistochemical technique. In addition expression of the enzyme was examined at the periphery of every myoma.
ISSN:0239-8508
1897-5631
DOI:10.5603/4341