首次青年缺血性卒中短期预后不良危险因素分析 Risk Factors for Short-term Poor Prognosis in Young Patients with First-ever Ischemic Stroke

目的 分析首次青年缺血性卒中患者出院、发病90d预后不良的相关危险因素。 方法 回顾性纳入18~45岁、发病72 h内的首次缺血性卒中患者,收集患者人口学信息、血管危险因素、实验室检查结果、入院和出院时NIHSS,以出院时和发病90 d mRS≥2分为预后不良,分别比较预后不良组和预后良好组危险因素的差异和病因分型特点,并采用多因素logistic回归分析出院和90 d预后不良的独立危险因素。 结果 研究共纳入691例首次青年缺血性卒中患者,出院预后不良234例(33.9%),90 d预后不良154例(22.3%)。出院时预后的独立危险因素包括入院时高NIHSS(OR 2.76,95%CI 2...

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Bibliographic Details
Published inZhongguo cuzhong zazhi Vol. 17; no. 6; pp. 600 - 604
Main Author 刘艳芳, 贾娇坤, 赵性泉
Format Journal Article
LanguageChinese
Published Editorial Department of Chinese Journal of Stroke 01.06.2022
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Summary:目的 分析首次青年缺血性卒中患者出院、发病90d预后不良的相关危险因素。 方法 回顾性纳入18~45岁、发病72 h内的首次缺血性卒中患者,收集患者人口学信息、血管危险因素、实验室检查结果、入院和出院时NIHSS,以出院时和发病90 d mRS≥2分为预后不良,分别比较预后不良组和预后良好组危险因素的差异和病因分型特点,并采用多因素logistic回归分析出院和90 d预后不良的独立危险因素。 结果 研究共纳入691例首次青年缺血性卒中患者,出院预后不良234例(33.9%),90 d预后不良154例(22.3%)。出院时预后的独立危险因素包括入院时高NIHSS(OR 2.76,95%CI 2.07~3.68,P <0.01),高LDL-C(OR 3.10,95%CI 1.01~9.51,P =0.04),独立保护因素高为TC(OR 0.37,95%CI 0.14~0.96,P =0.04)。90 d预后不良的独立危险因素包括入院时高NIHSS(OR 2.42,95%CI 1.79~3.28,P <0.01)和高Hcy(OR 1.02,95%CI 1.01~1.04,P =0.04)。 结论 入院时NIHSS升高、LDL-C升高、TC降低是青年缺血性卒中患者出院时预后的独立危险因素,而90 d预后的独立危险因素为入院时NIHSS升高和Hcy升高。 Objective To investigate the risk factors for short-term poor outcome (at discharge and 90-day follow-up) among the young adults with first-ever ischemic stroke. Methods Patients with first-ever ischemic stroke within 72 hours aged 18 to 45 years were enrolled in this retrospective study. Demographic information, vascular risk factors, laboratory tests results, NIHSS scores at admission and discharge were collected. Poor outcome was defi
ISSN:1673-5765
DOI:10.3969/j.issn.1673-5765.2022.06.008