Research progress on the role of bilirubin in inflammatory bowel disease

The role of bilirubin in inflammatory bowel disease is not only functioned as an antioxidant and anti-inflammatory factor, but also functioned in immune regulation, anti-platelet aggregation, and as inhibition factor of digestive protease and remodeling of microbiota. Serum bilirubin level is correl...

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Bibliographic Details
Published inJi chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics Vol. 42; no. 12; pp. 1925 - 1929
Main Author SHI Li, YUAN Hao, LIU Min, ZHENG Ya, WANG Yu-ping, GUO Qing-hong
Format Journal Article
LanguageChinese
Published Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College 01.12.2022
Subjects
bilirubin|inflammatory bowel disease|crohn disease|ulcerative colitis
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Summary:The role of bilirubin in inflammatory bowel disease is not only functioned as an antioxidant and anti-inflammatory factor, but also functioned in immune regulation, anti-platelet aggregation, and as inhibition factor of digestive protease and remodeling of microbiota. Serum bilirubin level is correlated with disease activity and severity, so is a potential serum marker of inflammatory bowel disease in terms of supporting clinical diagnosis and treatment of inflammatory bowel disease.
ISSN:1001-6325
DOI:10.16352/j.issn.1001-6325.2022.12.1925