Molecular aspects of bladder cancer

One of the most important objectives of genetic markers of cancer will be the possible identification of individuals at greatest  risk in order to allow better management and prognosis. Many urological tumors were associated to various types of gene alterations with a great number of genes involved...

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Published inEinstein (São Paulo, Brazil) Vol. 9; no. 1; pp. 95 - 99
Main Authors Gelbert Luiz Chamon do Carmo Amorim, Denny Fabricio Magalhães Veloso, José Carlos Vieira, Paulo Roberto Alves
Format Journal Article
LanguageEnglish
Published Instituto Israelita de Ensino e Pesquisa Albert Einstein 01.03.2011
Subjects
Urinary bladder neoplasms/genetics
Urinary bladder/pathology
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Summary:One of the most important objectives of genetic markers of cancer will be the possible identification of individuals at greatest  risk in order to allow better management and prognosis. Many urological tumors were associated to various types of gene alterations with a great number of genes involved in the process, hindering gene therapy. This treatment uses specific techniques and one or several genes are manipulated in the laboratory in order to  induce molecular alterations that may block the oncogenic process. The article addresses these issues emphasizing the importance of the new molecular biology techniques.
ISSN:1679-4508