Application of single-cell RNA sequencing technologies in aortic dilatation diseases

Aortic dilation disease, represented by aortic dissection and aortic aneurysm, is the most dangerous disease in vascular surgery. The pathogenesis of this disease is not very clear. Single-cell RNA sequencing (scRNA-seq) technology can study cell heterogeneity and identify new cell states and popula...

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Published inJi chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics Vol. 42; no. 7; pp. 1139 - 1143
Main Author ZHENG Kai, REN Hua-liang, ZHANG Wang-de, LI Chun-min
Format Journal Article
LanguageChinese
Published Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College 01.07.2022
Subjects
aortic disease|single-cell rna sequencing|single-cell transcriptome sequencing|high throughput rna sequencing
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Summary:Aortic dilation disease, represented by aortic dissection and aortic aneurysm, is the most dangerous disease in vascular surgery. The pathogenesis of this disease is not very clear. Single-cell RNA sequencing (scRNA-seq) technology can study cell heterogeneity and identify new cell states and populations at the single cell level, which provides a new tool for studying the occurrence and development mechanism of aortic disease.
ISSN:1001-6325
DOI:10.16352/j.issn.1001-6325.2022.07.1139