脑动脉前循环串联病变临床治疗效果meta分析Meta-analysis of Clinical Outcomes of Treatment for Anterior Circulation Tandem Lesions

• Published in: Zhongguo cuzhong zazhi Vol. 17; no. 5; pp. 503 - 509
• Main Author: 张彤, 王安心, 安媛, 张亚清, 刘艳芳, 赵性泉
• Format: Journal Article
• Language: Chinese
• Published: Editorial Department of Chinese Journal of Stroke 01.05.2022
• Subjects: anterior circulation tandem lesion; ischemic cerebrovascular disease; meta-analysis; meta分析; prognosis; 前循环串联病变; 缺血性脑血管病; 预后
• ISSN: 1673-5765
• DOI: 10.3969/j.issn.1673-5765.2022.05.011

Objective To compare the differences in clinical outcomes of different treatments for anterior circulation tandem lesions. Methods Databases including PubMed, Cochrane Library, ScienceDirect, CNKI, VIP, and Wanfang were retrieved from inception to December 11, 2021 to search for the literatures involving interventional treatment for anterior circulation tandem lesions in patients with acute ischemic stroke. The patients were divided into the intervention group and control group. Treatment strategy in intervention group was simultaneous emergency interventional treatment of both lesions, including thrombectomy or thrombolysis combined with stenting, and treatment strategy in control group was first interventional treatment of the responsible lesion, including thrombectomy or thrombolysis combined with stenting, and then selective treatment of the other lesion. The clinical outcomes including technical recanalization (TICI≥2b) rate, 90-day good prognosis (mRS score of 0-2), and mortality rate were compared betw