Comparison of e-test Values for Standard Antibiotics and Conventional Antimicrobial Assay Values for Ethanoic Acids against Nosocomial Multidrugresistant Pseudomonas aeruginosa

The present study aimed to determine the susceptibility of Pseudomonas aeruginosa strains isolated from patients with nosocomial infections to standard synthetic chemical antibiotics and organic ethanoic acids derived from local produce. The minimum inhibitory concentrations (MIC) of the standard sy...

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Published inJournal of pure & applied microbiology : an international research journal of microbiology Vol. 14; no. 1; pp. 255 - 260
Main Authors Muazzam Sheriff Maqbul, Ali Mohamed Alshabi, Aejaz A. Khan, S.M. Shakeel Iqubal, Tasneem Mohammed, Ibrahim Ahmed Shaikh, Areej Dawoud, Uday M. Muddapur, Mohammed Shahid Hussain, S.K. Singh
Format Journal Article
LanguageEnglish
Published Journal of Pure and Applied Microbiology 01.03.2020
Subjects
antimicrobial activity
ethanoic acid
immuno suppressed
nosocomial infection
pseudomonas aeroginosa
vinegar
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Summary:The present study aimed to determine the susceptibility of Pseudomonas aeruginosa strains isolated from patients with nosocomial infections to standard synthetic chemical antibiotics and organic ethanoic acids derived from local produce. The minimum inhibitory concentrations (MIC) of the standard synthetic antibiotics determined from standard e-test results and antibiotic sensitivity tests showed many multidrug-resistant strains among the isolates. We compared the susceptibility of these strains to organic ethanoic acids derived from different sources using standard microbiological assays. All strains of P. aeruginosa isolated from the patients were susceptible to the organic ethanoic acids with a satisfactory MIC and minimum bactericidal concentrations. Therefore, organic ethanoic acids were more effective against P. aeruginosa than standard synthetic antibiotics.
ISSN:0973-7510
2581-690X
DOI:10.22207/JPAM.14.1.26