Research progress of transcription factor AP-2 γ in malignant tumors

Transcription factor AP-2γ regulates not only the genetic procedures that control the proliferation and differentiation of trophoblast cells during early embryonic development, but also is the key target in the development of breast cancer, lung cancer, testicular cancer, melanoma and pancreatic can...

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Bibliographic Details
Published inJi chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics Vol. 42; no. 12; pp. 1955 - 1959
Main Author CHEN Kang, CHENG Fan
Format Journal Article
LanguageChinese
Published Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College 01.12.2022
Subjects
transcription factor|ap-2γ|embryonic development|tumor
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Summary:Transcription factor AP-2γ regulates not only the genetic procedures that control the proliferation and differentiation of trophoblast cells during early embryonic development, but also is the key target in the development of breast cancer, lung cancer, testicular cancer, melanoma and pancreatic cancer, thus affecting the occurrence and development of tumors. Therefore, paying attention to the regulatory mechanisms of AP-2γ in the occurrence and development of malignant tumors may provide new ideas for the diagnosis and treatment of tumors.
ISSN:1001-6325
DOI:10.16352/j.issn.1001-6325.2022.12.1955