MEMBRANE LEc EXPRESSION IN BREAST CANCER CELLS

Affine chromatography was used to isolate Lec antibodies from the sera of a healthy female donor with the high titers of these anti- bodies, which were labeled with biotin. The study enrolled 51 patients with primary breast cancer (BC). Antigen expression was found by immunohistochemistry and flow c...

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Published inOpukholi zhenskoĭ reproduktivnoĭ sistemy no. 3-4; pp. 43 - 48
Main Authors Ya. A. Udalova, N. V. Bovin, P. S. Obukhova, N. V. Shilova, A. M. Kovrigina, A. A. Subbotina, V. V. Timoshenko, O. E. Galanina, Z. G. Kadagidze, V. P. Letyagin, N. N. Tupitsyn
Format Journal Article
LanguageRussian
Published ABV-press 01.09.2014
Subjects
antibodies
breast cancer
lec
membrane expression
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Summary:Affine chromatography was used to isolate Lec antibodies from the sera of a healthy female donor with the high titers of these anti- bodies, which were labeled with biotin. The study enrolled 51 patients with primary breast cancer (BC). Antigen expression was found by immunohistochemistry and flow cytometry. With these two techniques being used, the detection rate of Lec expression in BC cells was 65% (33/51); the antigen was most frequently found by flow cytometry as compared with immunohistochemistry: 72 and 58% of cases, respectively.
ISSN:1994-4098
1999-8627
DOI:10.17650/1994-4098-2009-0-3-4-43-48