Design and baseline characteristics of a population-based birth cohort in Shanghai

• Published in: Shanghai Yufang Yixue Vol. 36; no. 1; pp. 11 - 15
• Main Authors: YU Huiting, CUI Xin, LIANG Zhou, CAI Renzhi, CHEN Lan, QIAN Naisi, LIN Weixiao, JIN Shan, WANG Chunfang, FU Chen
• Format: Journal Article
• Language: Chinese
• Published: Shanghai Preventive Medicine Association 01.01.2024
• Subjects: assisted reproductive technology; baseline characteristic; birth cohort; information technology; natural conception; reproductive health
• ISSN: 1004-9231
• DOI: 10.19428/j.cnki.sjpm.2024.23141

ObjectiveTo introduce the basic design， development plan and objectives of a population-based birth cohort in Shanghai， and further present the main data and baseline characteristics of enrolled participants in the cohort， and to provide key information for reproductive health-related studies.MethodsThe Shanghai population-based birth cohort initiated on January 1， 2005， included newborns born in Shanghai every year and their parents， and collected information on reproductive health， reproductive treatment， birth characteristics， growth and development status， as well as the incidence， treatment and death of diseases by employing data linkage technology and investigations. This formed a birth cohort spanning the entire life cycle.ResultsAs of October 2022， a total of 2 978 538 newborns and their parents were included in the cohort. Among them， 2 905 135 （97.54%） were naturally conceived （NC）， and 73 403 （2.46%） were born through assisted reproductive technologies （ART）. The average age of parents was （32.56±4