Study on preoperative radiotherapy in conversion therapy for patients with primary retroperitoneal soft tissue sarcoma difficult to resect or unresectable

• Published in: Waike Lilun yu Shijian Vol. 27; no. 6; pp. 530 - 533
• Main Author: PAN Xiangou, ZHANG Li, HOU Jiazhou, DU Shisuo, ZENG Zhaochong, WANG Binliang
• Format: Journal Article
• Language: Chinese
• Published: Editorial Office of Journal of Surgery Concepts & Practice 01.11.2022
• Subjects: retroperitoneal soft tissue sarcoma|radiotherapy|rate of conversion to resection
• ISSN: 1007-9610
• DOI: 10.16139/j.1007-9610.2022.06.010

Objective: To investigate the effect of preoperative radiotherapy in the patients with primary retroperitoneal soft tissue sarcoma difficult to resect or unresectable and recognize the results of radiotherapy associated with resection and the effect of treatment on prognosis. Methods: It was analyzed retrospectively with 44 cases of primary retroperitoneal soft tissue sarcoma difficult to resect or unresectable in Department of Radiation Oncology, Zhongshan Hospital from May 2017 to February 2022. Intensity modulated radiation therapy (IMRT) and helical tomotherapy (TOMO) were used to treat the patients, and the effects of conversion to resection treatment for patients with the prognosis and complications were analyzed. Results: A total of 44 cases received radiotherapy including 30 cases with IMRT and 14 cases with TOMO. The adverse events of radiotherapy were grade 1 to 2. After preoperative radiotherapy, 12 cases achieved partial response, 26 cases remained in stable condition and 6 cases progressed. There