Modern aspects of angina treatment in arterial hypertension patients: emphasizing endothelial function role

This literature review is analyzing heart rate (HR) role in the pathogenesis of arterial hypertension (AH) and coronary heart disease (CHD), together with HR prognostic role in assessing cardiovascular event risk. Modern approaches to pharmaceutical CHD treatment in Stage I-II AH patients, are analy...

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Published inKardiovaskuli͡a︡rnai͡a︡ terapii͡a︡ i profilaktika Vol. 7; no. 2; pp. 109 - 116
Main Authors L. L. Kirichenko, A. N. Golosova, S. V. Gatsura, A. P. Korolev, P. P. Struchkov, Zh. D. Dvoryanchikova
Format Journal Article
LanguageRussian
Published SILICEA-POLIGRAF» LLC 01.04.2008
Subjects
артериальная гипертония
дисфункция эндотелия
ивабрадин
ишемическая болезнь сердца
микроциркуляция
периндоприл
частота сердечных сокращений
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Summary:This literature review is analyzing heart rate (HR) role in the pathogenesis of arterial hypertension (AH) and coronary heart disease (CHD), together with HR prognostic role in assessing cardiovascular event risk. Modern approaches to pharmaceutical CHD treatment in Stage I-II AH patients, are analyzed from the evidence-based medicine point of view. Antianginal and antihypertensive agents' effects on endothelial function and microcirculation in this clinical group are discussed. The recent information on HR-decelerating medications' effects on stable angina clinical course and prognosis is presented. The authors justify the need for further investigation of ivabradine role in combined pharmaceutical treatment of cardiovascular disease.
ISSN:1728-8800
2619-0125