Safety analysis of immediate breast reconstruction with deep inferior epigastric perforator after neoadjuvant treatment

• Published in: Waike Lilun yu Shijian Vol. 28; no. 2; pp. 147 - 151
• Main Author: GAO Weiqi, ZHANG Xu, WANG Zheng, ZHU Yifei, HUANG Jiahui, HONG Jin, ZHU Siji, CHEN Xiaosong, HUANG Ou, HE Jianrong, CHEN Weiguo, LI Yafen, SHEN Kunwei, XU Hua, WU Jiayi
• Format: Journal Article
• Language: Chinese
• Published: Editorial Office of Journal of Surgery Concepts & Practice 01.03.2023
• Subjects: breast cancer|breast reconstruction|neoadjuvant treatment|deep inferior epigastric perforator
• ISSN: 1007-9610
• DOI: 10.16139/j.1007-9610.2023.02.11

Objective To evaluate the safety of immediate breast reconstruction using deep inferior epigastric perforator (DIEP) flaps in the patients after neoadjuvant treatment. Methods From January 2019 to February 2021, the data of patients with breast cancer undergoing total mastectomy and immediate breast reconstruction using DIEP flap in Comprehensive Breast Health Center, Department of General Surgery, Ruijin Hospital were collected. Comparison of clinicopathological features was done between neoadjuvant treatment group and control group. Univariate analysis was used to compare the rate of surgical complications between two groups. Results A total of 110 patients were enrolled with 23 cases (20.9%) in neoadjuvant treatment group and 87 cases (79.1%) in control group. None of carcinoma in situ (0 vs. 19.5%, P=0.003) and higher pTNM stage (P<0.001) was present in neoadjuvant treatment group compared with those in control group. However, there were no significant differences in the number of flap perforator of DIEP