Diagnostic value of determination of baseline concentrations of С-reactive protein and interleukin-6 in blood to assess the risk of cardiovascular disease

• Published in: Medicinskij vestnik Ûga Rossii no. 3; pp. 86 - 91
• Main Authors: M. I. Nazheva, I. A. Demidov
• Format: Journal Article
• Language: English
• Published: State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation 01.09.2015
• Subjects: screening, cardiovascular risk, markers of inflammation, diagnostic significance
• ISSN: 2219-8075; 2618-7876
• DOI: 10.21886/2219-8075-2015-3-86-91

Purpose: to identify the diagnostic value of simultaneous determination of baseline concentrations of С-reactive protein (CRP) and interleukin-6 levels in the blood in patients as additional factors in assessing the risk of cardiovascular disease by screening by specifying the intensity of inflammation.Materials and methods: screening to identify cardiovascular risk and the concentration in the blood CRP and interleukin-6 in 304 patients urban populations in the outpatient polyclinic inspection and survey.Results: set pairing between the increased risk on a scale SCORE, and the concentration of CRP in the blood. Diagnostic level of CRP in the blood to separate the risk of cardiovascular disease at the lowest and the highest was 3 mg/l. a closer link was established between the number of risk factors and the studied marker of inflammation.Summary: when screening risk assessment should be carried out in the cardiovascular disease with quantitative measurement of CRP in the blood concentrations of the base.