Protective effects of saffron, safranal and crocin administration on vitamins (A, D, E, K) and protein carbonyl levels against CCI4- induced oxidative damage in rats

Objective: The possible effects of saffron and its active components on oxidative stress are known. Protein carbonyls (PCO), formed due to protein exposure to oxidizing agents, are a newly researched topic. In this study, it was aimed to determine, antioxidant fatsoluble vitamins (A, D, E, K) and PC...

Full description

Saved in:
Bibliographic Details
Published inMarmara Medical Journal
Main Authors Bakır, Ahmet, Yıldız, Damla, Ekin, Suat, Oto, Gokhan, Aras, İbrahim, Bayram, İrfan
Format Journal Article
LanguageEnglish
Published 17.05.2024
Online AccessGet full text

Cover

More Information
Summary:Objective: The possible effects of saffron and its active components on oxidative stress are known. Protein carbonyls (PCO), formed due to protein exposure to oxidizing agents, are a newly researched topic. In this study, it was aimed to determine, antioxidant fatsoluble vitamins (A, D, E, K) and PCO values after saffron, safranal and crocin administration with carbon tetrachloride (CCl4) in rats. Materials and Methods: Fifty-four Wistar albino male rats were randomly selected, and 9 groups of n=6 were formed. Vitamin levels in rat serum were determined by HPLC and PCO levels were determined by spectrophotometric method. Results: A significant difference (p
ISSN:1019-1941
DOI:10.5472/marumj.1571808