ORAL PEMPHIGUS VULGARIS: A CASE REPORT

Pemphigus vulgaris is an autoimmune blistering disease clinically presenting as vesicles, bullae and erosion on the skin and mucous membrane. Histopathologically, it is characterized by acantholy­sis and supra basilar split. The underlying mechanism causing intra epithelial split in pemphigus vulgar...

Full description

Saved in:
Bibliographic Details
Published inJournal of Chitwan Medical College Vol. 10; no. 1; pp. 91 - 93
Main Authors Baral, Radha, Ojha, Bidhata, Bajracharya, Dipshikha
Format Journal Article
LanguageEnglish
Published 14.03.2020
Online AccessGet full text

Cover

More Information
Summary:Pemphigus vulgaris is an autoimmune blistering disease clinically presenting as vesicles, bullae and erosion on the skin and mucous membrane. Histopathologically, it is characterized by acantholy­sis and supra basilar split. The underlying mechanism causing intra epithelial split in pemphigus vulgaris is binding of IgG autoantibodies to desmoglin 3 which belongs to a transmembrane gly­coprotein adhesion molecule. Here we present a case of 27 years old male patient suffering from pemphigus vulgaris. This Case report highlights the importance of detailed case history, thorough clinical examination and appropriate investigation to reach a diagnosis of vesiculobullous lesion.
ISSN:2091-2412
2091-2889
DOI:10.54530/jcmc.137