Development and characterization of hydralazine mouth dissolving tablet

• Published in: International journal of health sciences pp. 7459 - 7469
• Main Authors: Dhone, Pravin G, Gundawar, Nilesh, Zopate, Pravin, Agrawalla, Dinesh
• Format: Journal Article
• Language: English
• Published: 08.08.2022
• ISSN: 2550-6978; 2550-696X
• DOI: 10.53730/ijhs.v6nS5.10700

Tablet dosage form is the most popular among all existing conventional dosage forms because of its convenience of self-administration, compactness and easy manufacturing. Many patients find it difficult to swallow tablets and capsules. The difficulty is experienced in particular by pediatric and geriatric patients, but it also applies to people who are ill on bed and to those active working patients who are busy or traveling, especially those who have no access to water. The drug hydralazine HCl were used. The amount of drug was 35 mg. the different super disintegrates was used to make a suitable mouth dissolving tablet. All the other reagents which is used in analytical grade reagents. In the present study mouth dissolving tablets of hydralazine HCl were designed, prepared and evaluated. These tablets can disintegrate or dissolve rapidly once placed into the oral cavity. The feofenadine was analyzed for its organoleptic, physicochemical and spectral (IR, UV) properties. The obtained hydralazine HCl was concordant with reference specifications. A complex of hydralazine HCl was successfully formulated. The volunteers rated the resinate as tasteless and agreeable complex.