Histopathological variation in thyroid dysfunction associated with musculoskeletal disorder patients

• Published in: International journal of health sciences pp. 7719 - 7726
• Main Authors: Raman, Ramendra Kumar, Mohanty, Biswa Bhusan, Das, Saurjya Ranjan, Panda, Sitansu Kumar
• Format: Journal Article
• Language: English
• Published: 03.05.2022
• ISSN: 2550-6978; 2550-696X
• DOI: 10.53730/ijhs.v6nS2.6914

Thyroid dysfunction has been associated with musculoskeletal disorders and there isan increased number of evidences that proves their association. Thyroid dysfunction especially in the form of hypo and hyperthyroidism has been linked to several connective tissue conditions. The primary objective of this study is to establish the histopathological variations in individuals with thyroid dysfunction with a musculoskeletal disorder.In this study with 300 subjects with a diagnosis of thyroid dysfunction, the histopathology of the thyroid tissues was analysed along with their variations.As a part of the histological findings, the following were analysed and evaluated. The hyperplasia of the synovial lining,cellularity of synovial stroma, inflammatory infiltrate, lymphoid follicles and vascularity were noted in muscle tissues. It was found that the histopathological variants increased as the severity of the thyroid dysfunction here in the case of hypothyroidism.