clinico-pathological study of primary intracranial neoplasms in a tertiary care hospital

• Published in: International journal of health sciences pp. 5818 - 5830
• Main Authors: Muddha, Sai Sudha, Anbumozhi, M. K, Gali, Vinutha
• Format: Journal Article
• Language: English
• Published: 23.04.2022
• ISSN: 2550-6978; 2550-696X
• DOI: 10.53730/ijhs.v6nS2.6480

Background: Central nervous system neoplasms represent a   unique, heterogeneous population of neoplasms and include both benign and malignant  tumours. The tumours of central nervous system are reported to be less than 2% of all malignancies. Aim: To study the frequency of intracranial tumours and their histopathological typing and their correlation with several clinical variables such as age, sex and clinical symptoms . Material & Methods: Study Design: Hospital based Prospective observational study. Study area: Dept. of. Pathology, Study Period: 2 years. Study population: patients who presented with signs and symptoms of primary intracranial tumours were examined and followed up for the histopathological diagnosis. Sample size: Study population consisted a total of 68 patients.  Sampling method: Simple Random sampling method. Inclusion criteria: Patients with both benign as well as malignant primary neoplasms of the brain including pituitary tumours. Exclusion criteria: All the spinal cord, calvarial and metastatic tumours were excluded. Ethical consideration: Institutional Ethical committee permission was taken prior to the commencement of the study. Study tools and Data collection procedure: Staining Procedures Adopted: After grossing, proper tissue bits were subjected for routine processing, fixation, dehydration, clearing and embedding in paraffin wax and blocks were made.