SYNTHESIS OF SOME NON-PROTEIN AMINO ACIDS DERIVED FROM SPIROHYDANTOINS

This article presents a synthesis of non-protein amino acids derived from 6- and 8- substituted cyclohexanespiro-5-hydantoins, spiro(adamantane-2',4'-imidazolidine)- 2,5-dione and 3',4'-dihydro-2H,2'H,5H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione. The target compou...

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Bibliographic Details
Published inJournal Scientific and Applied Research Vol. 10; no. 1; pp. 39 - 46
Main Author N. Marinov, Marin
Format Journal Article
LanguageEnglish
Published 11.11.2016
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Summary:This article presents a synthesis of non-protein amino acids derived from 6- and 8- substituted cyclohexanespiro-5-hydantoins, spiro(adamantane-2',4'-imidazolidine)- 2,5-dione and 3',4'-dihydro-2H,2'H,5H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione. The target compounds were prepared by an alkaline hydrolysis of the corresponding spirohydantoins with barium hydroxide. The products obtained were characterized by physicochemical parameters, IR , 1H and 13C NMR spectral data.
ISSN:1314-6289
2815-4622
DOI:10.46687/jsar.v10i1.204