Effect of Combined Oral Contraceptive Pill on FVC, FEV1 and FEV1/FVC

• Published in: Journal of Bangladesh Society of Physiologist Vol. 10; no. 1; pp. 21 - 25
• Main Authors: Islam, Farhana, Jahan, Nasim, Sultana, Nayma
• Format: Journal Article
• Language: English
• Published: 21.08.2015
• ISSN: 1995-1213
• DOI: 10.3329/jbsp.v10i1.24613

Background: Combined oral contraceptive pill (COCP) is the most commonly used contraceptive method in Bangladesh. This COCP may have some effects on different organs including lungs.Objective: To observe the effects of combined oral contraceptive pill (COCP) on FVC, FEV1 and FEV1/ FVC% in apparently healthy women receiving COCP.Methods: This cross sectional study was carried out in the Department of Physiology, Sir Salimullah Medical College (SSMC), Dhaka between July 2013 and June 2014. A total 30 apparently healthy young women, age ranged 20 to 30 years were included in this study who were combined oral contraceptive pill users (COCP-U) for at least 6 months. Thirty age and BMI matched combined oral contraceptive pill nonusers (COCP-NU) were taken as control. FVC, FEV1 and FEV1/FVC% of all the subjects were measured by digital spirometer. Statistical analysis was done by Independent sample ‘t’ test.Results: FVC (p<0.001), FEV1 (p<0.001) were significantly higher whereas, FEV1/FVC% (p<0.05) was significantly lower in COCP-U than those of COCP-NU. Moreover, the mean serum estrogen (p<0.001) and progesterone (p<0.05) levels were also significantly higher in COCP-U in comparison to those of COCP-NU.Conclusion: From the result of this study it can be concluded that COCP have beneficial effects on some pulmonary function parameters.Bangladesh Soc Physiol. 2015, June; 10(1): 21-25