INDUCING ABORTION IN 2ND TRIMESTER EFFICACY OF MISOPROSTOL WITH PREVIOUS ONE CESAREAN SECTION

• Published in: The professional medical journal Vol. 24; no. 6; pp. 839 - 842
• Main Authors: Ashraf, Saima, Sahar, Amara, Safdar, Sohail
• Format: Journal Article
• Language: English
• Published: 05.06.2017
• ISSN: 1024-8919; 2071-7733
• DOI: 10.29309/TPMJ/2017.24.06.1120

Objectives: To determine the efficacy of misoprostol for inducing the abortionin 2nd trimester with previous one cesarean section. Study Design: Descriptive case series.Place and Duration of Study: Department of Obstetrics & Gynaecology, Nishtar MedicalCollege and Hospital Multan from May, 2015 to October 2015. Material and Methods: Thesample included 139 patients having pervious one cesarean section with gestational age 14-20wks assessed on ultrasound and having an indication for termination of pregnancy like IUD,fetal anomalies (neural anomaly, cardiac anomaly), medical disorder hypertension, diabetesmellitus. General physical examination was done by the researcher. Investigations includingcomplete blood count, complete urine examination, random blood sugar, liver and kidneyfunction tests, coagulation profile were carried out. The researcher placed misoprostol 200μgper vaginally every 4 hourly with overnight rest maximum for 72 hours. Efficacy of misoprostolwas judged in terms of success rate in achieving termination. Termination of pregnancy wasconsidered successfully if cervical os progressively dilated and both fetus and placenta expelledwithin 72 hours after insertion of 1st dose of misoprostol without surgical intervention. Results.A total of 139 cases fulfilling the inclusion criteria were enrolled to determine the efficacy ofmisoprostol for inducing abortion in 2nd trimester with previous one cesarean section. Amongthese patients 84.89% (n=118) were treated effectively, 15.11% (n=21) were not effectivelytreated. Conclusion: Misoprostol for inducing the abortion in 2nd trimester with previous onecesarean section is effective for expulsion of the fetus and placenta.