INFLUENCE OF PHENSUCCINAL AND ITS METABOLITES ON CARBOHYDRATE AND ENERGY METABOLISM AT RATS IN THE CONDITIONS OF SUBCHRONIC EXPERIMENT

It studied the effects of Phensuccinal and its I phase’s metabolites on carbohydrate metabolism and bioenergetic processes in rats. We found that Phensuccinal influence at effective dose proved to intensification of glycolysis and increased activity of energy metabolism key enzymes — succinatedehydr...

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Published inProblems of Endocrine Pathology Vol. 42; no. 4; pp. 109 - 115
Main Authors Kudria, M. Y., Palagina, I. A., Mishenko, T. V., Ustenko, N. V., Pavlenko, T. A., Zhurakovskaya, M. V.
Format Journal Article
LanguageEnglish
Published 25.12.2012
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Summary:It studied the effects of Phensuccinal and its I phase’s metabolites on carbohydrate metabolism and bioenergetic processes in rats. We found that Phensuccinal influence at effective dose proved to intensification of glycolysis and increased activity of energy metabolism key enzymes — succinatedehydrogenase and cytochrom–c–oxidase. We concluded that Phensuccinal active metabolites can made contribution to these changes considering one-pointedness of the effects under its isolated administration in equimolar doses
ISSN:2227-4782
2518-1432
DOI:10.21856/j-PEP.2012.4.17