INFLUENCE OF PHENSUCCINAL AND ITS METABOLITES ON CARBOHYDRATE AND ENERGY METABOLISM AT RATS IN THE CONDITIONS OF SUBCHRONIC EXPERIMENT
It studied the effects of Phensuccinal and its I phase’s metabolites on carbohydrate metabolism and bioenergetic processes in rats. We found that Phensuccinal influence at effective dose proved to intensification of glycolysis and increased activity of energy metabolism key enzymes — succinatedehydr...
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Published in | Problems of Endocrine Pathology Vol. 42; no. 4; pp. 109 - 115 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
25.12.2012
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Online Access | Get full text |
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Summary: | It studied the effects of Phensuccinal and its I phase’s metabolites on carbohydrate metabolism and bioenergetic processes in rats. We found that Phensuccinal influence at effective dose proved to intensification of glycolysis and increased activity of energy metabolism key enzymes — succinatedehydrogenase and cytochrom–c–oxidase. We concluded that Phensuccinal active metabolites can made contribution to these changes considering one-pointedness of the effects under its isolated administration in equimolar doses |
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ISSN: | 2227-4782 2518-1432 |
DOI: | 10.21856/j-PEP.2012.4.17 |