Topical Application of Platelet-Rich Fibrin Liquid as a Novel and Minimally Invasive Treatment for Post-Gingival Depigmentation: A Case Report

• Published in: KnE Medicine pp. 190 - 199
• Main Authors: Sari, Rezmelia, Agung Wibawa, Abizar
• Format: Journal Article
• Language: English
• Published: 25.04.2022
• ISSN: 2519-125X; 2519-125X
• DOI: 10.18502/kme.v2i1.10851

Background: Gingival depigmentation is a common perio–esthetic surgery which results in extensive open wounds, discomfort and increased risk of infection. Cellulosebased periodontal dressing (CBP) can protect the wound, has less toxicity than Coe-Pak but no curative effect. Platelet-rich fibrin (PRF) membrane has been shown to accelerate wound healing after gingival depigmentation, but it requires suturing which causes patient discomfort. A simple and minimally invasive technique is needed to optimize the use of PRF which is convenient for both the operator and the patient. Objective: To investigate post-gingival depigmentation outcome – wound healing, pain and post-surgical complaint – after PRF liquid application compared to CBP. Case Report: A 24-year-old male presented with a complaint of blackish gum that affected his self-confidence. The patient had a history of smoking for the last five years. Gingival depigmentation was carried out using a scalpel followed by the application of CBP (right) and PRF liquid (left). Evaluation was done using the Visual Analogue Scale (VAS) and the Healing Index (HI) on days 3, 7 and 14 after depigmentation, followed by evaluation using the Adobe Photoshop CS2. Results: On day 3, the PRF HI was higher than that of the CBP. No postoperative complaint in the PRF group and the VAS score was similar. Conclusion: The results suggest that PRF liquid provides better post-gingival depigmentation healing than CBP on the third day post treatment. Furthermore, utilization of PRF liquid is expected to be an alternative for minimally invasive open wounds management especially post-gingival depigmentation. Keywords: gingival pigmentation, platelet-rich fibrin liquid, cellulose-based periodontal dressing, wound healing, case report